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Cocaine Toothache Drops: When Cocaine Was Sold for Toothaches

July 3, 2026 by Dr. Eeks

In the late 1800s, cocaine wasn’t just legal, it was found in a variety of medicines. One of the more surprising examples was cocaine toothache drops, which were sold over the counter to relieve dental pain.

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The reason they worked was straightforward: cocaine is a powerful local anesthetic. It numbs nerves and constricts blood vessels, temporarily easing tooth pain.

Advertisements from the era even featured children happily playing outside while promoting “Cocaine Toothache Drops! Instantaneous Cure! Price 15 cents.” Today, it’s difficult to imagine a product like that being marketed to families.

As doctors and public health officials learned more about cocaine’s addictive potential and health risks, attitudes changed. The early 20th century brought increasing regulation of cocaine-containing products, culminating in laws that severely restricted their sale and medical use.

Eeks’ Take

History has a funny way of humbling us.

Products that once seemed perfectly ordinary can look shocking a century later. Cocaine toothache drops remind us that medicine evolves as evidence accumulates, and that today’s accepted treatments may one day seem just as surprising.

It makes me wonder what OUR generation’s “cocaine toothache drops” are. ;)

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Here’s this reel on Instagram.

Tiktok

Here’s this reel on Tiktok:

@dr..eeks

In this episode of Public Health is Weird: In the the late 1800s & early 1900s, “Cocaine Toothache Drops” were sold over the counter to relieve tooth 🦷 pain. Cocaine works as a local anesthetic, so it temporarily numbed the pain. One advertisement even featured children playing outside while promising an “Instantaneous Cure” for their toothaches for just 15 cents. Different time. Different regulations. Different ads. 😉 What do you think? 🤔 If you like the Public Health is Weird series, I hope you follow! 🙏😊 #sciencetok #publichealth #healthtok #didyouknow

♬ original sound – Dr. EeKS

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Category: Public Health is WeirdTag: Causes Or Cures Podcast, cocaine for toothaches, historical trivia, kids took cocaine for toothaches, medical trivia, public health history, public health is weird, Public Health is Weird series

Dr. Eeks

Dr. Eeks runs BloomingWellness.com, exploring strange and trending health stories through a public health lens. She also hosts the Causes or Cures podcast. Join her weekly newsletter for weird public health, new research, and podcast updates.

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